questionText: To ask the Secretary of State for Health and Social Care, with reference to the policy paper entitled Replacing animals in science: A strategy to support the development, validation and uptake of alternative methods, published on 11 November 2025, what progress he has made on defining and applying guidance that permits first in human clinical trial submission for biological therapies where no pharmacologically relevant preclinical animal model exists based only on non-animal data.
answerText: In line with the Government’s strategy to replace animals in science, the Medicines and Healthcare products Regulatory Agency (MHRA) supports the use of non-animal approaches where they are fit for purpose and accepts that, where a biological product is n...
heading: Animal Experiments